Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
PTCH1 Q13635 patched 1 1.00 0.398 0.885
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
CDH1 P12830 cadherin 1 0.15 0.401 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
EDNRA P25101 endothelin receptor type A G-protein coupled receptor 0.99 0.426 0.885
BMP4 P12644 bone morphogenetic protein 4 Signaling 0.96 0.422 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
FLNB O75369 filamin B 6.1E-10 0.458 0.923