Disease: Primary sclerosing cholangitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PSC Cholangitis, primary sclerosing 0.603 0.731
AIRE O43918 autoimmune regulator 4.0E-12 0.516 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
ALB P02768 albumin Transporter 0.64 0.317 0.962
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
HLA-DOA P06340 major histocompatibility complex, class II, DO alpha Immune response 3.0E-10 0.509 0.808
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
DLAT P10515 dihydrolipoamide S-acetyltransferase 2.3E-08 0.576 0.731
CD28 P10747 CD28 molecule 0.36 0.436 0.885
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923