Disease: Parkinsonism, Juvenile
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ATP1A3 P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 1.00 0.544 0.615
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLC30A10 Q6XR72 solute carrier family 30 member 10 Transporter 0.98 0.578 0.654
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
PRKCD Q05655 protein kinase C delta Kinase 1.00 0.480 0.846
PRKRA O75569 protein activator of interferon induced protein kinase EIF2AK2 Kinase 0.42 0.579 0.615
PINK1 Q9BXM7 PTEN induced kinase 1 Kinase 1.9E-10 0.516 0.769
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
ALDH1A1 P00352 aldehyde dehydrogenase 1 family member A1 Enzyme 0.95 0.460 0.846
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
GCH1 P30793 GTP cyclohydrolase 1 Enzyme 0.90 0.511 0.846
GSR P00390 glutathione-disulfide reductase Enzyme 1.3E-06 0.494 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
ALDH1A2 O94788 aldehyde dehydrogenase 1 family member A2 Enzyme 0.36 0.578 0.692
SYNJ1 O43426 synaptojanin 1 Enzyme 0.43 0.576 0.577
PARK7 Q99497 Parkinsonism associated deglycase Enzyme 0.75 0.535 0.808
CBLL2 Q8N7E2 Cbl proto-oncogene like 2 Enzyme 0.476 0.808
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500