Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
TAC1 | P20366 | tachykinin precursor 1 | 0.75 | 0.424 | 0.923 | |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
SPG7 | Q9UQ90 | SPG7 matrix AAA peptidase subunit, paraplegin | Enzyme | 2.0E-36 | 0.436 | 0.885 |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
TPO | P07202 | thyroid peroxidase | Enzyme | 1.8E-21 | 0.455 | 0.846 |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
TET2 | Q6N021 | tet methylcytosine dioxygenase 2 | 4.3E-54 | 0.458 | 0.808 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
DNM1L | O00429 | dynamin 1 like | Enzyme modulator | 5.7E-04 | 0.475 | 0.808 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
ASXL1 | Q8IXJ9 | ASXL transcriptional regulator 1 | 1.3E-14 | 0.482 | 0.808 |