Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808