Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SLCO6A1 Q86UG4 solute carrier organic anion transporter family member 6A1 Transporter 2.9E-11 0.412 0.885
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GSTK1 Q9Y2Q3 glutathione S-transferase kappa 1 1.9E-06 0.412 0.885
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
SPG7 Q9UQ90 SPG7 matrix AAA peptidase subunit, paraplegin Enzyme 2.0E-36 0.436 0.885
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846