Disease: Progressive supranuclear palsy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
DNAJB1 P25685 DnaJ heat shock protein family (Hsp40) member B1 3.9E-02 0.597 0.692
DNAJB1P1 DnaJ heat shock protein family (Hsp40) member B1 pseudogene 1 0.650 0.654
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
IL6 P05231 interleukin 6 0.32 0.248 0.962
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923