Disease: Mental deterioration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ADCYAP1 P18509 adenylate cyclase activating polypeptide 1 Signaling 0.52 0.510 0.846
AKR1C4 P17516 aldo-keto reductase family 1 member C4 Enzyme 2.2E-17 0.587 0.846
ANGPT1 Q15389 angiopoietin 1 Signaling 0.95 0.446 0.808
AP5Z1 O43299 adaptor related protein complex 5 subunit zeta 1 7.3E-31 0.700 0.346
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
ATP13A2 Q9NQ11 ATPase cation transporting 13A2 9.0E-09 0.566 0.577
ATP1A3 P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 1.00 0.544 0.615
ATXN7 O15265 ataxin 7 0.96 0.581 0.654
ATXN8OS P0DMR3 ATXN8 opposite strand lncRNA 0.650 0.423
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
CALB1 P05937 calbindin 1 Calcium-binding protein 0.24 0.606 0.615
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CHAT P28329 choline O-acetyltransferase Enzyme 5.6E-11 0.520 0.808
CLN3 Q13286 CLN3 lysosomal/endosomal transmembrane protein, battenin Transporter 1.3E-07 0.572 0.692
COASY Q13057 Coenzyme A synthase Enzyme 8.1E-10 0.551 0.654
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923