Disease: Motor symptoms
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
ATP1A3 P13637 ATPase Na+/K+ transporting subunit alpha 3 Transporter 1.00 0.544 0.615
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C19orf12 Q9NSK7 chromosome 19 open reading frame 12 0.34 0.641 0.615
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CTSC P53634 cathepsin C Enzyme 1.1E-07 0.541 0.731
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
EEF1A2 Q05639 eukaryotic translation elongation factor 1 alpha 2 Enzyme 1.00 0.554 0.808
FMR1 Q06787 FMRP translational regulator 1 Nucleic acid binding 0.65 0.473 0.769
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
GRM4 Q14833 glutamate metabotropic receptor 4 G-protein coupled receptor 0.99 0.636 0.500
HTT P42858 huntingtin 1.00 0.548 0.654
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MCF2L O15068 MCF.2 cell line derived transforming sequence like Signaling 2.7E-07 0.559 0.769