Source: ALL
Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
CD274 | Q9NZQ7 | CD274 molecule | Receptor | 1.9E-02 | 0.324 | 0.923 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
VDR | P11473 | vitamin D receptor | Nuclear receptor | 1.7E-05 | 0.352 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
FGFR2 | P21802 | fibroblast growth factor receptor 2 | Kinase | 1.00 | 0.380 | 0.808 |
CDKN1B | P46527 | cyclin dependent kinase inhibitor 1B | 0.62 | 0.409 | 0.769 | |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
GATA3 | P23771 | GATA binding protein 3 | 0.90 | 0.415 | 0.846 | |
PGR | P06401 | progesterone receptor | Nuclear receptor | 5.1E-02 | 0.426 | 0.885 |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
MIB1 | Q86YT6 | mindbomb E3 ubiquitin protein ligase 1 | Enzyme | 3.4E-88 | 0.438 | 0.769 |
CYP1B1 | Q16678 | cytochrome P450 family 1 subfamily B member 1 | Enzyme | 2.2E-05 | 0.457 | 0.769 |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CYP17A1 | P05093 | cytochrome P450 family 17 subfamily A member 1 | 2.6E-04 | 0.462 | 0.769 | |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 |