Disease: Leishmaniasis, Visceral
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
LECT2 O14960 leukocyte cell derived chemotaxin 2 Signaling 1.5E-03 0.653 0.500
LGALS1 P09382 galectin 1 Signaling 4.5E-03 0.435 0.846
CXCL9 Q07325 C-X-C motif chemokine ligand 9 Signaling 2.9E-03 0.462 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
CXCR1 P25024 C-X-C motif chemokine receptor 1 G-protein coupled receptor 3.0E-07 0.508 0.769
CXCR2 P25025 C-X-C motif chemokine receptor 2 G-protein coupled receptor 1.4E-02 0.445 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962