Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
CYP1A1 P04798 cytochrome P450 family 1 subfamily A member 1 Enzyme 1.1E-17 0.436 0.846
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
HNF4A P41235 hepatocyte nuclear factor 4 alpha Nuclear receptor 0.15 0.461 0.808
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808