Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
ABCB6 Q9NP58 ATP binding cassette subfamily B member 6 (Langereis blood group) Transporter 8.6E-19 0.431 0.885
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPA5 P11021 heat shock protein family A (Hsp70) member 5 0.77 0.434 0.885
ELANE P08246 elastase, neutrophil expressed Enzyme 1.2E-03 0.447 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
SRY Q05066 sex determining region Y Transcription factor 0.456 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
PRDX2 P32119 peroxiredoxin 2 Enzyme 8.7E-02 0.474 0.885
SYNE1 Q8NF91 spectrin repeat containing nuclear envelope protein 1 3.2E-52 0.511 0.846
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
ATXN1 P54253 ataxin 1 0.97 0.534 0.769
ATXN3 P54252 ataxin 3 Enzyme 0.11 0.521 0.808
ARHGEF2 Q92974 Rho/Rac guanine nucleotide exchange factor 2 1.00 0.502 0.769
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
FLVCR1 Q9Y5Y0 FLVCR heme transporter 1 Transporter 1.3E-03 0.529 0.885
GRM1 Q13255 glutamate metabotropic receptor 1 G-protein coupled receptor 0.14 0.528 0.808
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
PNPLA6 Q8IY17 patatin like phospholipase domain containing 6 Enzyme 1.9E-13 0.533 0.769
PNKP Q96T60 polynucleotide kinase 3'-phosphatase 3.7E-14 0.553 0.692