Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
HMGB1 | P09429 | high mobility group box 1 | Nucleic acid binding | 0.82 | 0.368 | 0.923 |
S100B | P04271 | S100 calcium binding protein B | Calcium-binding protein | 4.4E-02 | 0.383 | 0.923 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
DMD | P11532 | dystrophin | 1.00 | 0.423 | 0.923 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
S100A1 | P23297 | S100 calcium binding protein A1 | Calcium-binding protein | 6.0E-03 | 0.421 | 0.846 |
FMR1 | Q06787 | FMRP translational regulator 1 | Nucleic acid binding | 0.65 | 0.473 | 0.769 |
P2RX7 | Q99572 | purinergic receptor P2X 7 | Ion channel | 3.3E-11 | 0.450 | 0.808 |
SCN1A | P35498 | sodium voltage-gated channel alpha subunit 1 | Ion channel | 1.00 | 0.477 | 0.808 |
NTRK2 | Q16620 | neurotrophic receptor tyrosine kinase 2 | Kinase | 1.00 | 0.479 | 0.808 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
RIPK1 | Q13546 | receptor interacting serine/threonine kinase 1 | Kinase | 7.9E-03 | 0.479 | 0.769 |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
ENO2 | P09104 | enolase 2 | Enzyme | 0.38 | 0.475 | 0.846 |
UCP2 | P55851 | uncoupling protein 2 | Transporter | 1.5E-10 | 0.493 | 0.808 |