Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
ARSA | P15289 | arylsulfatase A | Enzyme | 1.1E-11 | 0.448 | 0.923 |
PLA2G6 | O60733 | phospholipase A2 group VI | Enzyme modulator | 2.5E-10 | 0.476 | 0.846 |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
NKX2-1 | P43699 | NK2 homeobox 1 | Transcription factor | 0.36 | 0.457 | 0.808 |
UCHL1 | P09936 | ubiquitin C-terminal hydrolase L1 | Enzyme | 0.99 | 0.482 | 0.885 |
TUBB3 | Q13509 | tubulin beta 3 class III | Cellular structure | 2.6E-10 | 0.486 | 0.808 |
EZR | P15311 | ezrin | Cellular structure | 0.18 | 0.476 | 0.808 |
SMC1A | Q14683 | structural maintenance of chromosomes 1A | 1.00 | 0.509 | 0.808 | |
LRRK2 | Q5S007 | leucine rich repeat kinase 2 | Kinase | 2.6E-30 | 0.510 | 0.808 |
GRIN2A | Q12879 | glutamate ionotropic receptor NMDA type subunit 2A | Ion channel | 1.00 | 0.522 | 0.808 |
PINK1 | Q9BXM7 | PTEN induced kinase 1 | Kinase | 1.9E-10 | 0.516 | 0.769 |
PSAP | P07602 | prosaposin | 0.99 | 0.532 | 0.846 | |
NSUN2 | Q08J23 | NOP2/Sun RNA methyltransferase 2 | Enzyme | 2.6E-04 | 0.559 | 0.846 |
PNKP | Q96T60 | polynucleotide kinase 3'-phosphatase | 3.7E-14 | 0.553 | 0.692 | |
KDM5B | Q9UGL1 | lysine demethylase 5B | Epigenetic regulator | 7.9E-15 | 0.532 | 0.731 |
PARK7 | Q99497 | Parkinsonism associated deglycase | Enzyme | 0.75 | 0.535 | 0.808 |
ATP13A2 | Q9NQ11 | ATPase cation transporting 13A2 | 9.0E-09 | 0.566 | 0.577 | |
PODXL | O00592 | podocalyxin like | 1.0E-03 | 0.551 | 0.731 |