Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
MYD88 Q99836 MYD88 innate immune signal transduction adaptor Enzyme modulator 0.12 0.414 0.923
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
LOX P28300 lysyl oxidase 0.99 0.447 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
LIG4 P49917 DNA ligase 4 4.2E-06 0.478 0.846
FTO Q9C0B1 FTO alpha-ketoglutarate dependent dioxygenase 8.4E-08 0.486 0.885
ARID1B Q8NFD5 AT-rich interaction domain 1B 1.00 0.503 0.846