Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |
NTRK1 | P04629 | neurotrophic receptor tyrosine kinase 1 | Kinase | 2.0E-06 | 0.422 | 0.808 |
WNT5A | P41221 | Wnt family member 5A | Signaling | 0.99 | 0.443 | 0.808 |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 |
ROR2 | Q01974 | receptor tyrosine kinase like orphan receptor 2 | Kinase | 1.2E-04 | 0.498 | 0.731 |
SYK | P43405 | spleen associated tyrosine kinase | Kinase | 1.00 | 0.475 | 0.808 |
RIT1 | Q92963 | Ras like without CAAX 1 | Enzyme modulator | 0.13 | 0.527 | 0.808 |
DVL1 | O14640 | dishevelled segment polarity protein 1 | Signaling | 3.7E-06 | 0.531 | 0.769 |
DVL3 | Q92997 | dishevelled segment polarity protein 3 | Signaling | 0.39 | 0.537 | 0.731 |
LZTR1 | Q8N653 | leucine zipper like transcription regulator 1 | 1.0E-92 | 0.547 | 0.808 | |
CENPJ | Q9HC77 | centromere protein J | Enzyme | 2.1E-27 | 0.546 | 0.846 |
FZD2 | Q14332 | frizzled class receptor 2 | G-protein coupled receptor | 0.65 | 0.558 | 0.654 |
DNAAF4 | Q8WXU2 | dynein axonemal assembly factor 4 | 9.7E-10 | 0.623 | 0.731 | |
CEP63 | Q96MT8 | centrosomal protein 63 | Cellular structure | 6.2E-25 | 0.666 | 0.500 |