Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PTPN11 Q06124 protein tyrosine phosphatase non-receptor type 11 1.00 0.385 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
PTCH1 Q13635 patched 1 1.00 0.398 0.885
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
WNT5A P41221 Wnt family member 5A Signaling 0.99 0.443 0.808
ATR Q13535 ATR serine/threonine kinase Kinase 3.5E-09 0.456 0.923
SOS1 Q07889 SOS Ras/Rac guanine nucleotide exchange factor 1 Enzyme modulator 1.00 0.485 0.808
ROR2 Q01974 receptor tyrosine kinase like orphan receptor 2 Kinase 1.2E-04 0.498 0.731
SYK P43405 spleen associated tyrosine kinase Kinase 1.00 0.475 0.808
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
DVL3 Q92997 dishevelled segment polarity protein 3 Signaling 0.39 0.537 0.731
LZTR1 Q8N653 leucine zipper like transcription regulator 1 1.0E-92 0.547 0.808
CENPJ Q9HC77 centromere protein J Enzyme 2.1E-27 0.546 0.846
FZD2 Q14332 frizzled class receptor 2 G-protein coupled receptor 0.65 0.558 0.654
DNAAF4 Q8WXU2 dynein axonemal assembly factor 4 9.7E-10 0.623 0.731
CEP63 Q96MT8 centrosomal protein 63 Cellular structure 6.2E-25 0.666 0.500