Disease: Myelodysplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
XRCC2 O43543 X-ray repair cross complementing 2 4.0E-07 0.512 0.731
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
UBE2T Q9NPD8 ubiquitin conjugating enzyme E2 T 1.1E-05 0.550 0.731
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
SLX4 Q8IY92 SLX4 structure-specific endonuclease subunit 1.6E-22 0.565 0.731
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SBDS Q9Y3A5 SBDS ribosome maturation factor Enzyme 6.2E-05 0.601 0.692
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RPS14 P62263 ribosomal protein S14 Nucleic acid binding 0.90 0.631 0.500
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
PIGA P37287 phosphatidylinositol glycan anchor biosynthesis class A 0.96 0.575 0.654
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
NUP98 P52948 nucleoporin 98 and 96 precursor Enzyme 1.00 0.532 0.577
NPM1 P06748 nucleophosmin 1 Chaperone 1.00 0.464 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
MLF1 P58340 myeloid leukemia factor 1 Signaling 4.4E-09 0.666 0.385
MAD2L2 Q9UI95 mitotic arrest deficient 2 like 2 8.2E-02 0.547 0.731
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923