Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | Signaling | 2.7E-04 | 0.310 | 0.962 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
IL2 | P60568 | interleukin 2 | 0.48 | 0.336 | 0.885 | |
ABCB1 | P08183 | ATP binding cassette subfamily B member 1 | Transporter | 1.3E-05 | 0.344 | 0.885 |
CCND1 | P24385 | cyclin D1 | Enzyme modulator | 0.89 | 0.344 | 0.923 |
H3P10 | H3 histone pseudogene 10 | 0.350 | 0.846 | |||
TLR2 | O60603 | toll like receptor 2 | 1.0E-06 | 0.361 | 0.923 | |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
MIR21 | microRNA 21 | 0.363 | 0.846 | |||
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
CSF3 | P09919 | colony stimulating factor 3 | 0.38 | 0.377 | 0.885 | |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
CD34 | P28906 | CD34 molecule | 5.0E-06 | 0.368 | 0.808 | |
MECP2 | P51608 | methyl-CpG binding protein 2 | Epigenetic regulator | 0.89 | 0.414 | 0.846 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
EZH2 | Q15910 | enhancer of zeste 2 polycomb repressive complex 2 subunit | Epigenetic regulator | 1.00 | 0.376 | 0.885 |