Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
SDHC | Q99643 | succinate dehydrogenase complex subunit C | 2.0E-04 | 0.517 | 0.846 | |
TSC1 | Q92574 | TSC complex subunit 1 | 1.00 | 0.440 | 0.808 | |
KLLN | B2CW77 | killin, p53 regulated DNA replication inhibitor | 5.1E-03 | 0.578 | 0.654 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
SEC23B | Q15437 | SEC23 homolog B, COPII coat complex component | Enzyme modulator | 6.1E-20 | 0.579 | 0.692 |
AKT1 | P31749 | AKT serine/threonine kinase 1 | Kinase | 0.98 | 0.311 | 0.962 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
SDHD | O14521 | succinate dehydrogenase complex subunit D | Transporter | 0.34 | 0.472 | 0.885 |