Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TGFB1 | P01137 | transforming growth factor beta 1 | Signaling | 3.7E-02 | 0.287 | 0.962 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ALB | P02768 | albumin | Transporter | 0.64 | 0.317 | 0.962 |
MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
BRCA1 | P38398 | BRCA1 DNA repair associated | Enzyme | 9.2E-29 | 0.367 | 0.923 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
GSTP1 | P09211 | glutathione S-transferase pi 1 | 1.4E-02 | 0.383 | 0.923 | |
SMAD4 | Q13485 | SMAD family member 4 | Transcription factor | 1.00 | 0.401 | 0.808 |
HPGDS | O60760 | hematopoietic prostaglandin D synthase | 1.8E-06 | 0.388 | 0.923 | |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
VWF | P04275 | von Willebrand factor | Enzyme modulator | 3.2E-25 | 0.408 | 0.885 |
CFTR | P13569 | CF transmembrane conductance regulator | Ion channel | 2.2E-58 | 0.424 | 0.885 |
TTR | P02766 | transthyretin | Transporter | 0.52 | 0.423 | 0.885 |
JAG1 | P78504 | jagged canonical Notch ligand 1 | 1.00 | 0.429 | 0.808 | |
HFE | Q30201 | homeostatic iron regulator | 2.6E-08 | 0.436 | 0.846 | |
XRCC1 | P18887 | X-ray repair cross complementing 1 | 6.3E-09 | 0.421 | 0.923 | |
INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
ADRB2 | P07550 | adrenoceptor beta 2 | G-protein coupled receptor | 0.53 | 0.442 | 0.923 |
HNF4A | P41235 | hepatocyte nuclear factor 4 alpha | Nuclear receptor | 0.15 | 0.461 | 0.808 |
ABCC8 | Q09428 | ATP binding cassette subfamily C member 8 | Transporter | 8.0E-24 | 0.474 | 0.846 |
OGG1 | O15527 | 8-oxoguanine DNA glycosylase | 3.9E-12 | 0.453 | 0.808 | |
HNF1A | P20823 | HNF1 homeobox A | Nucleic acid binding | 0.96 | 0.478 | 0.846 |