Disease: Primary sclerosing cholangitis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB11 O95342 ATP binding cassette subfamily B member 11 Transporter 1.6E-12 0.566 0.654
ABCB4 P21439 ATP binding cassette subfamily B member 4 Transporter 2.2E-07 0.529 0.615
ALB P02768 albumin Transporter 0.64 0.317 0.962
FGF19 O95750 fibroblast growth factor 19 Signaling 0.57 0.548 0.615
GGTLC1 Q9BX51 gamma-glutamyltransferase light chain 1 Enzyme 3.3E-05 0.559 0.731
GPBAR1 Q8TDU6 G protein-coupled bile acid receptor 1 G-protein coupled receptor 1.4E-09 0.548 0.731
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
HLA-A P04439 major histocompatibility complex, class I, A 1.3E-03 0.370 0.846
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-C P10321 major histocompatibility complex, class I, C 1.6E-06 0.415 0.846
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
LOC102724197 inactive glutathione hydrolase 2 0.559 0.731
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
NR1H4 Q96RI1 nuclear receptor subfamily 1 group H member 4 Nuclear receptor 9.4E-04 0.513 0.808
NR1I2 O75469 nuclear receptor subfamily 1 group I member 2 Nuclear receptor 7.3E-09 0.418 0.846
PNPLA3 Q9NST1 patatin like phospholipase domain containing 3 Enzyme 5.7E-08 0.556 0.692
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846