Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NOD2 Q9HC29 nucleotide binding oligomerization domain containing 2 Enzyme 2.0E-30 0.423 0.923
NLRP12 P59046 NLR family pyrin domain containing 12 3.6E-28 0.569 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MEFV O15553 MEFV innate immuity regulator, pyrin 1.0E-14 0.440 0.885
NLRC4 Q9NPP4 NLR family CARD domain containing 4 9.9E-12 0.556 0.769
NT5E P21589 5'-nucleotidase ecto Enzyme 2.3E-11 0.436 0.885
ADA2 Q9NZK5 adenosine deaminase 2 Enzyme 8.1E-08 0.545 0.846
GEMIN2 O14893 gem nuclear organelle associated protein 2 Nucleic acid binding 1.5E-06 0.597 0.654
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
AIMP2 Q13155 aminoacyl tRNA synthetase complex interacting multifunctional protein 2 8.0E-03 0.393 0.923
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
SLC9A3R2 Q15599 SLC9A3 regulator 2 3.8E-02 0.588 0.654
EBI3 Q14213 Epstein-Barr virus induced 3 Signaling 0.11 0.474 0.808
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923