Disease: Polycystic Ovary Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HSD17B2 P37059 hydroxysteroid 17-beta dehydrogenase 2 Enzyme 1.8E-10 0.656 0.385
GREB1 Q4ZG55 growth regulating estrogen receptor binding 1 6.6E-09 0.663 0.385
SRD5A1 P18405 steroid 5 alpha-reductase 1 Enzyme 1.2E-05 0.631 0.538
CCNE2 O96020 cyclin E2 Enzyme modulator 0.87 0.608 0.538
ERRFI1 Q9UJM3 ERBB receptor feedback inhibitor 1 1.2E-02 0.612 0.538
AKR1C2 P52895 aldo-keto reductase family 1 member C2 Enzyme 6.9E-11 0.608 0.577
UCN2 Q96RP3 urocortin 2 3.8E-02 0.633 0.577
AKR1C1 Q04828 aldo-keto reductase family 1 member C1 Enzyme 3.5E-15 0.593 0.615
HSD17B1 P14061 hydroxysteroid 17-beta dehydrogenase 1 Enzyme 1.3E-04 0.610 0.615
SRD5A2 P31213 steroid 5 alpha-reductase 2 Enzyme 0.564 0.615
FBLN1 P23142 fibulin 1 0.92 0.587 0.654
FSHR P23945 follicle stimulating hormone receptor G-protein coupled receptor 1.4E-11 0.539 0.654
GNRHR P30968 gonadotropin releasing hormone receptor G-protein coupled receptor 6.8E-02 0.540 0.654
HOXA10 P31260 homeobox A10 0.88 0.538 0.692
IGFBP6 P24592 insulin like growth factor binding protein 6 Enzyme modulator 2.9E-02 0.601 0.692
PAPPA Q13219 pappalysin 1 0.16 0.558 0.692
PRLR P16471 prolactin receptor Signaling 0.99 0.572 0.692
RUNX3 Q13761 RUNX family transcription factor 3 Transcription factor 0.84 0.459 0.731
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731
MSTN O14793 myostatin Signaling 0.51 0.528 0.731
NR4A1 P22736 nuclear receptor subfamily 4 group A member 1 Nuclear receptor 0.37 0.490 0.731
NCOR1 O75376 nuclear receptor corepressor 1 Transcription factor 1.00 0.597 0.731
FST P19883 follistatin Enzyme modulator 0.98 0.513 0.731
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769
AREG P15514 amphiregulin Signaling 0.35 0.487 0.769