Disease: Impulsive Behavior
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1A O00555 calcium voltage-gated channel subunit alpha1 A Ion channel 1.00 0.489 0.769
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DNAJC13 O75165 DnaJ heat shock protein family (Hsp40) member C13 1.00 0.682 0.577
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
HCN1 O60741 hyperpolarization activated cyclic nucleotide gated potassium channel 1 1.00 0.564 0.654
HNMT P50135 histamine N-methyltransferase 2.0E-02 0.579 0.808
HTRA2 O43464 HtrA serine peptidase 2 3.6E-03 0.542 0.692
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
LRP2 P98164 LDL receptor related protein 2 1.00 0.491 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MCF2L O15068 MCF.2 cell line derived transforming sequence like Signaling 2.7E-07 0.559 0.769
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
PANK2 Q9BZ23 pantothenate kinase 2 Kinase 7.4E-07 0.559 0.808
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
SLC1A2 P43004 solute carrier family 1 member 2 Transporter 0.71 0.511 0.731
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SMS P52788 spermine synthase 0.97 0.491 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
VPS35 Q96QK1 VPS35 retromer complex component Transporter 0.97 0.656 0.500