Disease: Inherited neuropathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPG11 Q96JI7 SPG11 vesicle trafficking associated, spatacsin 1.6E-39 0.576 0.538
TDP1 Q9NUW8 tyrosyl-DNA phosphodiesterase 1 Enzyme 1.3E-17 0.612 0.538
TRPV4 Q9HBA0 transient receptor potential cation channel subfamily V member 4 Ion channel 2.2E-16 0.457 0.808
APTX Q7Z2E3 aprataxin Nucleic acid binding 4.0E-10 0.590 0.500
MAD2L1BP Q15013 MAD2L1 binding protein 1.4E-08 0.623 0.577
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
MTMR2 Q13614 myotubularin related protein 2 Enzyme 3.0E-07 0.659 0.538
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HINT1 P49773 histidine triad nucleotide binding protein 1 Enzyme 1.8E-03 0.619 0.577
TWNK Q96RR1 twinkle mtDNA helicase Enzyme 3.2E-03 0.516 0.692
HSPB8 Q9UJY1 heat shock protein family B (small) member 8 4.3E-02 0.570 0.577
MPZ P25189 myelin protein zero 0.27 0.503 0.846
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
GJB1 P08034 gap junction protein beta 1 Cell-cell junction 0.85 0.514 0.731
PMP22 Q01453 peripheral myelin protein 22 Cellular structure 0.91 0.471 0.885
PLP1 P60201 proteolipid protein 1 Cellular structure 0.93 0.543 0.769
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
LMNA P02545 lamin A/C 1.00 0.384 0.885
ATP7A Q04656 ATPase copper transporting alpha Transporter 1.00 0.494 0.769
KIF5A Q12840 kinesin family member 5A Cellular structure 1.00 0.593 0.731
KIF1B O60333 kinesin family member 1B Cellular structure 1.00 0.516 0.808