Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
LMNA | P02545 | lamin A/C | 1.00 | 0.384 | 0.885 | |
CTLA4 | P16410 | cytotoxic T-lymphocyte associated protein 4 | 0.94 | 0.369 | 0.923 | |
POLG | P54098 | DNA polymerase gamma, catalytic subunit | Enzyme | 2.1E-09 | 0.457 | 0.846 |
TTR | P02766 | transthyretin | Transporter | 0.52 | 0.423 | 0.885 |
TRPV4 | Q9HBA0 | transient receptor potential cation channel subfamily V member 4 | Ion channel | 2.2E-16 | 0.457 | 0.808 |
PRKN | O60260 | parkin RBR E3 ubiquitin protein ligase | Enzyme | 6.9E-07 | 0.431 | 0.846 |
HSPB1 | P04792 | heat shock protein family B (small) member 1 | 2.8E-07 | 0.436 | 0.808 | |
CD28 | P10747 | CD28 molecule | 0.36 | 0.436 | 0.885 | |
ATP7A | Q04656 | ATPase copper transporting alpha | Transporter | 1.00 | 0.494 | 0.769 |
PMP22 | Q01453 | peripheral myelin protein 22 | Cellular structure | 0.91 | 0.471 | 0.885 |
MFN2 | O95140 | mitofusin 2 | Enzyme | 0.99 | 0.471 | 0.846 |
HSPB3 | Q12988 | heat shock protein family B (small) member 3 | 6.1E-05 | 0.448 | 0.769 | |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
LIG4 | P49917 | DNA ligase 4 | 4.2E-06 | 0.478 | 0.846 | |
HSPB2 | Q16082 | heat shock protein family B (small) member 2 | 3.3E-04 | 0.457 | 0.769 | |
MPZ | P25189 | myelin protein zero | 0.27 | 0.503 | 0.846 | |
NEFL | P07196 | neurofilament light | 0.488 | 0.769 | ||
TWNK | Q96RR1 | twinkle mtDNA helicase | Enzyme | 3.2E-03 | 0.516 | 0.692 |
MUL1 | Q969V5 | mitochondrial E3 ubiquitin protein ligase 1 | 1.9E-06 | 0.473 | 0.808 | |
CBLL2 | Q8N7E2 | Cbl proto-oncogene like 2 | Enzyme | 0.476 | 0.808 | |
CD80 | P33681 | CD80 molecule | 1.1E-02 | 0.475 | 0.769 | |
ATP6 | P00846 | ATP synthase F0 subunit 6 | Transporter | 0.541 | 0.731 | |
GJB1 | P08034 | gap junction protein beta 1 | Cell-cell junction | 0.85 | 0.514 | 0.731 |
BAG3 | O95817 | BAG cochaperone 3 | 0.62 | 0.498 | 0.846 | |
CD86 | P42081 | CD86 molecule | 0.95 | 0.483 | 0.769 |