Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
KMT2A | Q03164 | lysine methyltransferase 2A | 1.00 | 0.410 | 0.885 | |
GPT | P24298 | glutamic--pyruvic transaminase | Enzyme | 3.6E-19 | 0.403 | 0.923 |
RAF1 | P04049 | Raf-1 proto-oncogene, serine/threonine kinase | Kinase | 0.85 | 0.418 | 0.885 |
CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
EP300 | Q09472 | E1A binding protein p300 | 1.00 | 0.459 | 0.846 | |
BRD4 | O60885 | bromodomain containing 4 | Epigenetic regulator | 1.00 | 0.446 | 0.885 |
ATR | Q13535 | ATR serine/threonine kinase | Kinase | 3.5E-09 | 0.456 | 0.923 |
SOS1 | Q07889 | SOS Ras/Rac guanine nucleotide exchange factor 1 | Enzyme modulator | 1.00 | 0.485 | 0.808 |
HDAC2 | Q92769 | histone deacetylase 2 | Epigenetic regulator | 1.00 | 0.476 | 0.846 |
SMC1A | Q14683 | structural maintenance of chromosomes 1A | 1.00 | 0.509 | 0.808 | |
HDAC8 | Q9BY41 | histone deacetylase 8 | Epigenetic regulator | 0.98 | 0.511 | 0.885 |
NIPBL | Q6KC79 | NIPBL cohesin loading factor | Nucleic acid binding | 1.00 | 0.521 | 0.808 |
SMC3 | Q9UQE7 | structural maintenance of chromosomes 3 | 1.00 | 0.535 | 0.846 | |
RAD21 | O60216 | RAD21 cohesin complex component | 1.00 | 0.528 | 0.846 | |
CTCF | P49711 | CCCTC-binding factor | Transcription factor | 1.00 | 0.504 | 0.769 |
RIT1 | Q92963 | Ras like without CAAX 1 | Enzyme modulator | 0.13 | 0.527 | 0.808 |
ANKRD11 | Q6UB99 | ankyrin repeat domain 11 | 1.00 | 0.556 | 0.808 | |
GRM1 | Q13255 | glutamate metabotropic receptor 1 | G-protein coupled receptor | 0.14 | 0.528 | 0.808 |
ARSD | P51689 | arylsulfatase D | Enzyme | 1.6E-03 | 0.535 | 0.808 |
SETD5 | Q9C0A6 | SET domain containing 5 | 1.00 | 0.560 | 0.731 | |
DYM | Q7RTS9 | dymeclin | 3.6E-13 | 0.563 | 0.769 |