Disease: Blindness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS10 Q9H324 ADAM metallopeptidase with thrombospondin type 1 motif 10 Enzyme 0.84 0.641 0.500
ADORA2A P29274 adenosine A2a receptor G-protein coupled receptor 0.60 0.526 0.769
AMD1 P17707 adenosylmethionine decarboxylase 1 Enzyme 0.98 0.593 0.577
AMD1P2 adenosylmethionine decarboxylase 1 pseudogene 2 0.608 0.538
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
C8orf37 Q96NL8 chromosome 8 open reading frame 37 2.4E-05 0.628 0.538
CCDC102B Q68D86 coiled-coil domain containing 102B 3.2E-16 0.821 0.154
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GNAT1 P11488 G protein subunit alpha transducin 1 Enzyme modulator 9.9E-13 0.666 0.308
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
MYOC Q99972 myocilin Cellular structure 7.6E-12 0.595 0.500
MYP2 myopia 2 (high grade, autosomal dominant) 0.659 0.308
NDP Q00604 norrin cystine knot growth factor NDP 0.65 0.566 0.692
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
PAX6 P26367 paired box 6 1.00 0.450 0.769
PDE6B P35913 phosphodiesterase 6B 2.6E-27 0.626 0.346
PLOD1 Q02809 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 Enzyme 1.5E-15 0.579 0.731
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
RBP3 P10745 retinol binding protein 3 1.1E-04 0.621 0.500
RHO P08100 rhodopsin G-protein coupled receptor 1.3E-04 0.525 0.769
RPE Q96AT9 ribulose-5-phosphate-3-epimerase 2.5E-04 0.575 0.538