Disease: Unspecified visual loss
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADAMTS10 Q9H324 ADAM metallopeptidase with thrombospondin type 1 motif 10 Enzyme 0.84 0.641 0.500
AMD1 P17707 adenosylmethionine decarboxylase 1 Enzyme 0.98 0.593 0.577
AMD1P2 adenosylmethionine decarboxylase 1 pseudogene 2 0.608 0.538
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
CYP1B1 Q16678 cytochrome P450 family 1 subfamily B member 1 Enzyme 2.2E-05 0.457 0.769
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
LTBP2 Q14767 latent transforming growth factor beta binding protein 2 Calcium-binding protein 7.4E-04 0.572 0.692
MYOC Q99972 myocilin Cellular structure 7.6E-12 0.595 0.500
MYP2 myopia 2 (high grade, autosomal dominant) 0.659 0.308
OPA1 O60313 OPA1 mitochondrial dynamin like GTPase Enzyme modulator 0.99 0.510 0.846
PAX6 P26367 paired box 6 1.00 0.450 0.769
PLXNA2 O75051 plexin A2 1.1E-06 0.447 0.808
PRDM5 Q9NQX1 PR/SET domain 5 3.6E-10 0.621 0.654
PROM1 O43490 prominin 1 Transporter 1.9E-22 0.410 0.846
RBP3 P10745 retinol binding protein 3 1.1E-04 0.621 0.500
RHO P08100 rhodopsin G-protein coupled receptor 1.3E-04 0.525 0.769
RPE Q96AT9 ribulose-5-phosphate-3-epimerase 2.5E-04 0.575 0.538
RPGR Q92834 retinitis pigmentosa GTPase regulator 1.00 0.536 0.692
TBC1D24 Q9ULP9 TBC1 domain family member 24 Enzyme modulator 1.3E-08 0.530 0.808
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
ZEB2 O60315 zinc finger E-box binding homeobox 2 Transcription factor 1.00 0.471 0.808
ZNF469 Q96JG9 zinc finger protein 469 0.72 0.584 0.769