Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
XRCC1 P18887 X-ray repair cross complementing 1 6.3E-09 0.421 0.923
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
GBA P04062 glucosylceramidase beta 1.4E-06 0.500 0.808
DNM1L O00429 dynamin 1 like Enzyme modulator 5.7E-04 0.475 0.808
SUFU Q9UMX1 SUFU negative regulator of hedgehog signaling 1.00 0.493 0.769
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
MKS1 Q9NXB0 MKS transition zone complex subunit 1 Extracellular structure 3.4E-16 0.505 0.769
AHI1 Q8N157 Abelson helper integration site 1 1.1E-25 0.513 0.846
TMEM67 Q5HYA8 transmembrane protein 67 2.1E-24 0.512 0.769
CEP290 O15078 centrosomal protein 290 1.1E-60 0.517 0.769
ITPR1 Q14643 inositol 1,4,5-trisphosphate receptor type 1 Ion channel 1.00 0.534 0.846
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
RPGRIP1L Q68CZ1 RPGRIP1 like Enzyme modulator 4.1E-31 0.534 0.769
CSPP1 Q1MSJ5 centrosome and spindle pole associated protein 1 3.3E-29 0.544 0.769
CC2D2A Q9P2K1 coiled-coil and C2 domain containing 2A 1.7E-27 0.532 0.692