Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
TLR2 O60603 toll like receptor 2 1.0E-06 0.361 0.923
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
NFKB1 P19838 nuclear factor kappa B subunit 1 Transcription factor 1.00 0.396 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
CASP1 P29466 caspase 1 Enzyme 3.5E-05 0.413 0.885
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
TBX1 O43435 T-box transcription factor 1 Transcription factor 0.84 0.433 0.808
RUNX2 Q13950 RUNX family transcription factor 2 Transcription factor 0.95 0.437 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
STS P08842 steroid sulfatase Enzyme 0.81 0.431 0.846
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846