Disease: Common Variable Immunodeficiency
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANP32B Q92688 acidic nuclear phosphoprotein 32 family member B Enzyme modulator 0.96 0.541 0.731
CARD9 Q9H257 caspase recruitment domain family member 9 8.1E-13 0.566 0.654
CD19 P15391 CD19 molecule 0.90 0.430 0.885
CD40LG P29965 CD40 ligand Signaling 0.72 0.414 0.846
CD86 P42081 CD86 molecule 0.95 0.483 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
FCGR2A P12318 Fc fragment of IgG receptor IIa Cell adhesion 2.0E-06 0.480 0.769
FCGR3A P08637 Fc fragment of IgG receptor IIIa Cell adhesion 3.7E-06 0.432 0.962
FCGRT P55899 Fc fragment of IgG receptor and transporter 4.1E-02 0.563 0.654
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
GEM P55040 GTP binding protein overexpressed in skeletal muscle 1.2E-08 0.467 0.769
IFNG P01579 interferon gamma 0.47 0.288 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL21 Q9HBE4 interleukin 21 0.63 0.441 0.769
IL23R Q5VWK5 interleukin 23 receptor Signaling 5.6E-04 0.466 0.769
IL33 O95760 interleukin 33 8.3E-10 0.409 0.885
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
IRF4 Q15306 interferon regulatory factor 4 Transcription factor 0.86 0.491 0.769
KIR2DS1 Q14954 killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1 Receptor 0.537 0.769
KIR3DL1 P43629 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Receptor 8.4E-14 0.475 0.769
KIR3DL2 P43630 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2 Receptor 6.1E-12 0.543 0.769
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846