Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
PLG P00747 plasminogen Enzyme 1.0E-02 0.389 0.923
CASP8 Q14790 caspase 8 Enzyme 3.7E-06 0.404 0.923
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
CD28 P10747 CD28 molecule 0.36 0.436 0.885
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
DCTN4 Q9UJW0 dynactin subunit 4 0.73 0.472 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808