Disease: Alzheimer Disease, Early Onset
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769
ABI3 Q9P2A4 ABI family member 3 Enzyme modulator 5.0E-05 0.716 0.231
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ARC Q7LC44 activity regulated cytoskeleton associated protein 0.59 0.573 0.769
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
ADAMTS1 Q9UHI8 ADAM metallopeptidase with thrombospondin type 1 motif 1 Enzyme 0.72 0.555 0.654
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
IDUA P35475 alpha-L-iduronidase Enzyme 3.8E-13 0.499 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
APBB1 O00213 amyloid beta precursor protein binding family B member 1 0.97 0.722 0.346
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ANXA1 P04083 annexin A1 1.2E-07 0.442 0.885
APOC1 P02654 apolipoprotein C1 0.22 0.581 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
ATP5F1A P25705 ATP synthase F1 subunit alpha Transporter 1.00 0.604 0.731
AMFR Q9UKV5 autocrine motility factor receptor 5.8E-05 0.599 0.692
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BAX Q07812 BCL2 associated X, apoptosis regulator Signaling 0.32 0.417 0.885
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769