Disease: Senile Plaques
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TAS2R62P taste 2 receptor member 62 pseudogene 0.729 0.192
APBB1 O00213 amyloid beta precursor protein binding family B member 1 0.97 0.722 0.346
LRP8 Q14114 LDL receptor related protein 8 1.00 0.644 0.346
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
NRGN Q92686 neurogranin 0.48 0.608 0.615
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SUCLA2 Q9P2R7 succinate-CoA ligase ADP-forming subunit beta Enzyme 2.3E-03 0.566 0.654
ITM2B Q9Y287 integral membrane protein 2B 0.63 0.617 0.654
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846