Disease: Senile Plaques
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
ADAM10 O14672 ADAM metallopeptidase domain 10 1.00 0.489 0.846
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
APBB1 O00213 amyloid beta precursor protein binding family B member 1 0.97 0.722 0.346
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CLU P10909 clusterin 7.8E-05 0.426 0.885
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSD P07339 cathepsin D Enzyme 9.2E-04 0.478 0.846
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
ENO2 P09104 enolase 2 Enzyme 0.38 0.475 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923