Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
SYT1 P21579 synaptotagmin 1 Transporter 0.60 0.412 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
S100A1 P23297 S100 calcium binding protein A1 Calcium-binding protein 6.0E-03 0.421 0.846