| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
| HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
| TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
| FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
| BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
| ERBB3 | P21860 | erb-b2 receptor tyrosine kinase 3 | Kinase | 1.7E-15 | 0.448 | 0.808 |
| CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
| PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
| MTOR | P42345 | mechanistic target of rapamycin kinase | Kinase | 1.00 | 0.343 | 0.885 |
| CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
| MAP2K1 | Q02750 | mitogen-activated protein kinase kinase 1 | Kinase | 0.90 | 0.439 | 0.846 |
| CNOT9 | Q92600 | CCR4-NOT transcription complex subunit 9 | 0.99 | 0.769 | 0.192 | |
| CREBBP | Q92793 | CREB binding protein | 1.00 | 0.428 | 0.808 | |
| FBXW7 | Q969H0 | F-box and WD repeat domain containing 7 | Enzyme modulator | 1.00 | 0.465 | 0.808 |