Disease: Metastatic melanoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
AQP1 P29972 aquaporin 1 (Colton blood group) Ion channel 2.6E-07 0.467 0.885
AXL P30530 AXL receptor tyrosine kinase Kinase 1.3E-02 0.489 0.615
B2M P61769 beta-2-microglobulin Immune response 0.56 0.447 0.846
BAP1 Q92560 BRCA1 associated protein 1 Enzyme 0.99 0.454 0.731
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BMPR1B O00238 bone morphogenetic protein receptor type 1B Kinase 1.00 0.573 0.615
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRSK1 Q8TDC3 BR serine/threonine kinase 1 Kinase 1.00 0.722 0.462
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
CD163 Q86VB7 CD163 molecule Enzyme 8.3E-04 0.427 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD276 Q5ZPR3 CD276 molecule Enzyme modulator 2.5E-09 0.505 0.731
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDK9 P50750 cyclin dependent kinase 9 Kinase 8.9E-05 0.498 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
CLDN7 O95471 claudin 7 Cell-cell junction 2.9E-03 0.494 0.808
COL18A1 P39060 collagen type XVIII alpha 1 chain 1.7E-10 0.449 0.808
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923