Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HPP1 hyperpigmentation, progressive, 1 0.686 0.346
ACVR1B P36896 activin A receptor type 1B Kinase 1.00 0.663 0.385
USP10 Q14694 ubiquitin specific peptidase 10 Enzyme 0.99 0.663 0.462
ACVR2A P27037 activin A receptor type 2A Kinase 1.00 0.636 0.615
ARID2 Q68CP9 AT-rich interaction domain 2 1.00 0.543 0.808
PDXP Q96GD0 pyridoxal phosphatase Enzyme 0.26 0.533 0.731
MUC2 Q02817 mucin 2, oligomeric mucus/gel-forming Enzyme modulator 9.4E-10 0.486 0.808
MUC5AC P98088 mucin 5AC, oligomeric mucus/gel-forming Enzyme modulator 1.0E-08 0.483 0.808
UGT1A1 P22309 UDP glucuronosyltransferase family 1 member A1 3.3E-06 0.464 0.769
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TWIST1 Q15672 twist family bHLH transcription factor 1 Transcription factor 0.34 0.397 0.846
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
HPGDS O60760 hematopoietic prostaglandin D synthase 1.8E-06 0.388 0.923
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923