Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
PTCH1 Q13635 patched 1 1.00 0.398 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
WNK1 Q9H4A3 WNK lysine deficient protein kinase 1 Kinase 1.00 0.416 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
CREBBP Q92793 CREB binding protein 1.00 0.428 0.808
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
CHD7 Q9P2D1 chromodomain helicase DNA binding protein 7 1.00 0.441 0.846
TSC2 P49815 TSC complex subunit 2 Enzyme modulator 1.00 0.439 0.808
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
SMARCA4 P51532 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Epigenetic regulator 1.00 0.450 0.885
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
KMT2D O14686 lysine methyltransferase 2D 1.00 0.465 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
SCN8A Q9UQD0 sodium voltage-gated channel alpha subunit 8 Ion channel 1.00 0.510 0.731
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
CUX1 P39880 Q13948 cut like homeobox 1 Transcription factor 1.00 0.465 0.846
COL1A2 P08123 collagen type I alpha 2 chain 1.00 0.486 0.846
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769