Disease: Achondroplasia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CNP P09543 2',3'-cyclic nucleotide 3' phosphodiesterase Enzyme 0.98 0.604 0.692
DCN P07585 decorin 0.31 0.457 0.808
EDN3 P14138 endothelin 3 Signaling 2.5E-02 0.608 0.577
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
SLC20A1 Q8WUM9 solute carrier family 20 member 1 Transporter 6.7E-02 0.582 0.577
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962