Disease: Adult Diffuse Large B-Cell Lymphoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
CD79A P11912 CD79a molecule Receptor 0.69 0.536 0.731
CD79B P40259 CD79b molecule Receptor 0.92 0.576 0.577
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
MCTS1 Q9ULC4 MCTS1 re-initiation and release factor Receptor 0.87 0.552 0.692
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MDM4 O15151 MDM4 regulator of p53 Nucleic acid binding 1.00 0.461 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769
NCL P19338 nucleolin Nucleic acid binding 1.00 0.509 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
NR1I3 Q14994 nuclear receptor subfamily 1 group I member 3 Nuclear receptor 3.5E-08 0.448 0.846
ABL2 P42684 ABL proto-oncogene 2, non-receptor tyrosine kinase Kinase 3.6E-07 0.619 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BTK Q06187 Bruton tyrosine kinase Kinase 1.00 0.464 0.808
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MST1R Q04912 macrophage stimulating 1 receptor Kinase 7.9E-37 0.542 0.808