Disease: Childhood B Acute Lymphoblastic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ATN1 P54259 atrophin 1 1.00 0.409 0.885
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
HOXA@ homeobox A cluster 0.599 0.654
IL2 P60568 interleukin 2 0.48 0.336 0.885
IL3RA P26951 interleukin 3 receptor subunit alpha Signaling 3.0E-27 0.560 0.769
IRX3 P78415 iroquois homeobox 3 Transcription factor 0.89 0.705 0.462
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PAX5 Q02548 paired box 5 1.00 0.487 0.654
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
SET Q01105 SET nuclear proto-oncogene Enzyme modulator 1.00 0.507 0.808
TRBV20OR9-2 T cell receptor beta variable 20/OR9-2 (non-functional) 0.403 0.923