Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
SMARCB1 Q12824 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Nucleic acid binding 1.00 0.434 0.846
NCAM1 P13591 neural cell adhesion molecule 1 1.00 0.415 0.885
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
FOXO1 Q12778 forkhead box O1 1.00 0.433 0.846
RB1 P06400 RB transcriptional corepressor 1 Nucleic acid binding 1.00 0.444 0.885
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
MIR221 microRNA 221 0.449 0.846