Disease: Adult Acute Myeloblastic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
KMT2A Q03164 lysine methyltransferase 2A 1.00 0.410 0.885
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
ERG P11308 ETS transcription factor ERG Transcription factor 0.96 0.453 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
PML P29590 promyelocytic leukemia 0.21 0.477 0.846
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
SALL4 Q9UJQ4 spalt like transcription factor 4 Transcription factor 1.00 0.489 0.769
GATA2 P23769 GATA binding protein 2 0.98 0.496 0.654
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
DEK P35659 DEK proto-oncogene 0.13 0.542 0.769