Disease: Grade III Childhood Astrocytoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769
DCX O43602 doublecortin 0.30 0.511 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
H3-3A P84243 H3.3 histone A 0.12 0.559 0.692
H3-3B P84243 H3.3 histone B 0.81 0.599 0.385
H3P10 H3 histone pseudogene 10 0.350 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
IGFBP2 P18065 insulin like growth factor binding protein 2 Enzyme modulator 0.12 0.478 0.769
MGMT P16455 O-6-methylguanine-DNA methyltransferase 1.2E-07 0.412 0.885
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TP73 O15350 tumor protein p73 Transcription factor 1.00 0.449 0.808
TSC22D1 Q15714 TSC22 domain family member 1 0.96 0.619 0.615
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923