Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
EGFR | P00533 | epidermal growth factor receptor | Kinase | 0.37 | 0.295 | 0.885 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CASP3 | P42574 | caspase 3 | Enzyme | 0.10 | 0.351 | 0.923 |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
COX8A | P10176 | cytochrome c oxidase subunit 8A | Enzyme | 0.12 | 0.400 | 0.846 |
NOS1 | P29475 | nitric oxide synthase 1 | 1.00 | 0.408 | 0.885 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
MGMT | P16455 | O-6-methylguanine-DNA methyltransferase | 1.2E-07 | 0.412 | 0.885 | |
IDH1 | O75874 | isocitrate dehydrogenase (NADP(+)) 1 | 2.6E-12 | 0.424 | 0.808 | |
IDH2 | P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 0.88 | 0.434 | 0.808 | |
DHDDS | Q86SQ9 | dehydrodolichyl diphosphate synthase subunit | Enzyme | 0.25 | 0.468 | 0.885 |
PDGFB | P01127 | platelet derived growth factor subunit B | Signaling | 0.77 | 0.488 | 0.846 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
STMN1 | P16949 | stathmin 1 | 7.5E-02 | 0.458 | 0.885 | |
MDM4 | O15151 | MDM4 regulator of p53 | Nucleic acid binding | 1.00 | 0.461 | 0.808 |
CHPT1 | Q8WUD6 | choline phosphotransferase 1 | Enzyme | 2.4E-04 | 0.474 | 0.846 |
IGFBP2 | P18065 | insulin like growth factor binding protein 2 | Enzyme modulator | 0.12 | 0.478 | 0.769 |
TCF12 | Q99081 | transcription factor 12 | Transcription factor | 0.68 | 0.565 | 0.654 |