Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
TSC2 | P49815 | TSC complex subunit 2 | Enzyme modulator | 1.00 | 0.439 | 0.808 |
SDHB | P21912 | succinate dehydrogenase complex iron sulfur subunit B | Enzyme | 2.4E-04 | 0.474 | 0.846 |
SLX4 | Q8IY92 | SLX4 structure-specific endonuclease subunit | 1.6E-22 | 0.565 | 0.731 | |
RPS6KA3 | P51812 | ribosomal protein S6 kinase A3 | Kinase | 1.00 | 0.491 | 0.846 |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
GALNT12 | Q8IXK2 | polypeptide N-acetylgalactosaminyltransferase 12 | Enzyme | 9.4E-07 | 0.780 | 0.269 |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
NLRP2 | Q9NX02 | NLR family pyrin domain containing 2 | 1.4E-38 | 0.515 | 0.731 | |
NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
MCF2L | O15068 | MCF.2 cell line derived transforming sequence like | Signaling | 2.7E-07 | 0.559 | 0.769 |
LRP2 | P98164 | LDL receptor related protein 2 | 1.00 | 0.491 | 0.846 | |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
GEN1 | Q17RS7 | GEN1 Holliday junction 5' flap endonuclease | 3.7E-15 | 0.682 | 0.500 | |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
DRD2 | P14416 | dopamine receptor D2 | G-protein coupled receptor | 0.75 | 0.436 | 0.846 |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |
C11orf65 | Q8NCR3 | chromosome 11 open reading frame 65 | 2.0E-14 | 0.670 | 0.462 | |
CHEK2 | O96017 | checkpoint kinase 2 | Kinase | 1.2E-24 | 0.460 | 0.808 |
CRLS1 | Q9UJA2 | cardiolipin synthase 1 | 3.1E-03 | 0.659 | 0.538 | |
BRCA3 | breast cancer 3 | 0.705 | 0.269 | |||
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |