Source: INFERRED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
SDHB P21912 succinate dehydrogenase complex iron sulfur subunit B Enzyme 2.4E-04 0.474 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
MAP2K2 P36507 mitogen-activated protein kinase kinase 2 Kinase 0.97 0.534 0.731
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
SEMA4A Q9H3S1 semaphorin 4A Signaling 1.8E-05 0.569 0.692
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
STK11 Q15831 serine/threonine kinase 11 Kinase 0.99 0.435 0.808
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
FAN1 Q9Y2M0 FANCD2 and FANCI associated nuclease 1 1.7E-25 0.610 0.577
CDC73 Q6P1J9 cell division cycle 73 1.00 0.543 0.615